While fibroids can develop at any age, their occurrence tends to rise as women age. Symptoms commonly surface in a woman's late 30s or early 40s and may persist until menopause. After menopause, the chance of developing new fibroids diminishes significantly, and existing ones usually shrink.

African American women face a threefold higher risk of developing uterine fibroids compared to women of other racial backgrounds. Additionally, younger African American women aged 29 to 39 often experience more severe symptoms. Studies suggest that genetics and low Vitamin D levels may play significant roles in this increased risk.

Being significantly overweight or having a high Body Mass Index (BMI) can elevate the risk of uterine fibroids. Excess fat cells produce higher amounts of estrogen, leading to increased hormone levels in the body, which can promote fibroid growth.

Women who begin menstruating at a younger age tend to have a higher prevalence of fibroids. Generally, girls experience their first period (menarche) around 12 or 13 years old. Research indicates that early menstruation correlates with higher risks of fibroids, obesity, and diabetes, with early menarche being more common among African American women.

There is often a genetic aspect to uterine fibroids, making family history a significant risk factor. If your mother, sister, or grandmother had fibroids, your risk of developing them may be elevated. In particular, if your mother had fibroids, your chances of developing them are three times greater than average.

Vitamin D is a fat-soluble vitamin that aids in the absorption and metabolism of calcium, magnesium, and phosphate. It also functions as a hormone due to its effects on the reproductive system. A deficiency in Vitamin D is indicated by levels below 30 ng/ml. Women with uterine fibroids typically have an average Vitamin D level of 23.3 ng/ml.